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125700-67-6
1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1)

Catalog#:1P000OYO

CAS:125700-67-6

MDL:MFCD00077413

Molecular Formula:C11H16BF4N5O++

Molecular Weight:321.0823

UN Number:

Haz Class:

Packing Group:

Synonyms: (1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; benzotriazol-1-yl-tetramethyluronium tetrafluoroborate; 2-(1h-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetra-fluoroborate; 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluroniumtetrafluoroborate; 2-(1H-benztriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(lH-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-[(1H)-benzotriazol-1-yl]-1,1,3,3-tetramethyl-uronium tetrafluoroborate; benzotriazol-1-yl-[bis(dimethylamino)methylene]oxonium tetrafluoroborate; N,N,N',N'-tetramethyl-O-(benzotriazole-1-yl)-uronium tetrafluoroborate; N,N,N',N'-Tetramethyl-O-(benzotriazole-1-yl)uronium tetrafluoroborate; O-(1H -benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; o-(1h benzotriazol-1-yl)-n,n,n',n'-tetramethyl-uronium tetrafluoroborate; N,N,N',N'-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate; o-(1h benzotriazol-1-yl)-n,n,n',n'-tetramethyluronium tetrafluoroborate; O-(1H-benzotriazol-1-yl) N,N, N',N'-tetramethyluronium tetrafluoroborate; O-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; O-(1H-benzotriazol-1-yl)-N,N, N',N'-tetramethyluronium tetrafluoroborate; O-(1H-benzotriazol-1-yl)-N,N,N', N'-tetramethyluronium tetrafluoroborate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyl-uronium tetrafluoroborate; O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluorborat; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoro-borate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluroniunn tetrafluorborat; o-(1h-benzotriazole-1-yl) n,n,n',n'-tetramethyl uronium tetrafluoroborate; o-(1h-benzotriazol-1-yl)-n,n,n',n'-tetramethyluronium tetrafluoroborate; O-(benzotriazol-1-yl)-1,1,3,3-tetramethyl uronium tetrafluoroborate; O-(Benzotriazol-1-yl)-N, N, N', N'-tetramethyluronium tetrafluoroborate; O-(benzotriazol-1-yl)-N,N,N', N'-tetramethyluronium tetrafluoroborate; o-(benzotriazol-1-yl)-n,n,n',n',-tetramethyluronium tetrafluoroborate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyl uronium tetrafluoroborate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyl-uronium tetrafluoroborate; O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%; O-(benzotriazole-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; O-Benzotriazol-1-yl-N,N,N;,N;-tetramethyluronium Tetrafluoroborate (TBTU); (benzotriazol-1-yloxy-dimethylamino-methylene)-dimethyl-ammonium tetrafluoroborate; o-(1h-benzotriazol-1-yl)-n,n,n',n'-tetramethyluroniumtetrafluoroborate; [(1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylidene]dimethylazanium tetrafluoroborate; [(benzotriazol-1-yloxy)-dimethylamino-methylene]-dimethyl-ammonium tetrafluoro borate; [(benzotriazol-1-yloxy)-dimethylamino-methylene]-dimethyl-ammonium tetrafluoroborate; [(benzotriazol-1-yloxy)-dimethylamino-methylene]dimethyl-ammonium tetrafluoroborate; [(benzotriazol-l-yloxy)-dimethylamino-methylene]-dimethyl-ammonium tetrafluoroborate; [benzotriazol-1-yloxy(dimethylamino)methylene]-dimethyl-ammonium tetrafluoroborate; [benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium tetrafluoroborate; O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, >=97.0% (N); [(1H-1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylidene]dimethylazanium; tetrafluoroboranuide; N-[(1H-1,2,3-benzotriazol-1-yloxy)(dimethylamino)-methylene]-N-methylmethanaminium tetrafluoroborate; o-(benzotriazol-1-yl)-n,n,n',n'-tetra methyluronium tetrafluoroborate; N-[(1H-1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methylmethanaminium tetrafluoroborate; N-[(1H-1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium tetrafluoroborate; N-[(1H-1,2,3-benzotriazol-1-yloxy)-(dimethylamino)methylene]-N-methylmethanaminium tetrafluoroborate; N-[(1H-1,2,3-benzotriazol-1yloxy)(dimethylamino)methylene]-N-methylmethanaminium tetrafluoroborate; N-[(1H-benzotriazol-1-yloxy)(dimethyl-amino)methylene]-N-methylmethanaminium tetrafluoroborate; N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methylmethanaminium tetrafluoro-borate; N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methylmethanaminium tetrafluoroborate; O-(Benzotriazol-1-yl)-N,N,N inverted exclamation mark ,N inverted exclamation mark -tetramethyluronium Tetrafluoroborate; Btttfb; C11H16N5O.BF4; o-(1h-benzotriazol-1-yl)-1,1,3,3-tetramethyl-uronium tetrafluoroborate; C11-H16-N5-O.B-F4; CID2733207; A7032; B1658; EC 423-040-4; EC 603-087-9; Benzotriazol-1-yl-tetramethyluronium tetrafluoroborate; O-Benzotriazolyl tetramethylisouronium tetrafluoroborate; Tetrazole, 3 To 4 Wt. % Solution In Acetonitrile 100ml; (1H-Benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; TBTU; [O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate]; 1-(Bis(dimethylamino)methylene)-1H-benzotriazol-1-ium 3-oxide tetrafluoroborate; 1-[bis(dimethylamino)methylene]-1H-benzotriazol-1-ium 3-oxide tetrafluoroborate; IUPAC: (benzotriazol-1-yloxy-dimethylamino-methylidene)-dimethyl-azanium; Tetrafluoroboron; O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99% 1g; O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 97% - 1G 1g; O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 97% - 5G 5g; O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99% - 25G 25g; BTU; TBTU 98% for synthesis O-(Benzotriazol-1-Yl)-N,N,N',N'-Tetramethyluronium Tetrafluoroborate store at 2-8?C 5gm; 2-(1h-benzo[d][1,2,3]triazol-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborate; TBTU;; JKEKMBGUVUKMQB-UHFFFAOYSA-N; BTTTFB; PubChem12754; AC1MBYD1; SCHEMBL44479; KSC174Q8B; ACMC-209b02; C11H16BF4N5O; CTK0H4880; ACT08049; BCP12819; ANW-18528; 125700-67-6; 2-(1-h-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; AKOS015832962; AKOS016001198; AM83863; AT-2944; MCULE-3125970269; RL01206; RTR-003827; AC-19131; AS-11819; TBTU; BC000805; BC215024; SC-11275; AB0001029; FT-0608370; ST24032317; ST51007233; TL80073609; B-2083; J-005267; 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; J-523817; F0001-0383; (benzotriazol-1-yloxy)bisdimethylaminomethylium fluoroborate; (benzotriazol-1-yloxy)bisdimethylaminomethyliumfluoroborate; (benzotriazol-1-yloxy)bisdimethylamino-methylium fluoroborate; 2-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIU; (benzotriazol-1-yl)-N,N,N',N'-tetramethyl-uronium tetrafluoroborate; (benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; 0-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluroniumtetrafluoroborate; 0-benzotriazol-1-yl-N,N,N',N'-tetramethyluronium tetrafluoroborate; 2-(1h-benzo[d][1,2,3]triazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 1H-benzotriazol-1-yl 1,1,3,3-tetramethyluronium tetrafluoroborate; 1H-benzotriazol-1-yl-1,1,3,3-tetramethyl uronium tetrafluoroborate; 2-(1h-benzotriazol-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(Benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-benzotriazol-1-yl-n,n,n',n'-tetramethyluronium tetrafluoroborate; benzotriazol-1-yl-N,N,N',N'-tetramethyluronium tetrafluoroborate; O-(benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluroniumtetrafluoroborate; O-(benzotriazol-1-yl)N,N,N',N'-tetramethyluronium tetrafluoroborate; o-(benzotriazol-1yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; o-(benztriazol-1-yl)n,n,n',n'-tetramethyluronium tetrafluorborate; O-Benzotrazol-1-yl-N,N,N',N'-tetramethyluronum tetrafluoroborate; o-benzotriazol-1-yl-n,n,n',n',-tetramethyluronium tetrafluoroborate; O-benzotriazol-1-yl-N,N,N',N'-tetra-methyluronium tetrafluoroborate; o-benzotriazol-1-yl-n,n,n'n'-tetramethyluroniumtetrafluoroborate; o-benzotriazol-1-yl-n,n,n,n-tetramethyluronium tetrafluoroborate; o-benzotriazol-1-yl-n.n,n',n'-tetramethyluronium tetrafluoroborate; o-benzotriazol-l-yl-N,N,N',N'-tetramethyluronium tetrafluoroborate; 0-(1H Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; 0-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; MFCD00077413; 0-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; 2(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1 H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1 H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1-H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1h benzotriazol-1-yl)-1,1,3,3,-tetramethyluronium tetrafluoroborate; 2-(1H-benzo triazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1H-benzo-triazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1h-benzotriazol-1-yl) -1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1h-benzotriazol-1-yl)-1,1,3,3,-tetramethyluronium tetrafluoroborate; o-benzotriazol-1-yl-n,n,n',n'-tetramethyluronium tetrafluoroborate; 2-(1h-benzotriazol-1-yl)-1,1,3,3,-tetramethyluroniumtetrafluoroborate; 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetra-methyluronium tetrafluoroborate; 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyl uronium tetrafluoroborat; 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyl uronium tetrafluoroborate; 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyl-uronium tetrafluoroborate; 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluroniumtetrafluoroborate; 2-(1H-benzotriazol-1-yl)1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1H-benzotriazol-1yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1H-benzotriazole-1-yl) 1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyl-uronium tetrafluoroborate;

Keywords: 125700-67-6,MFCD00077413,1P000OYO,1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1),C11H16BF4N5O++

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Catalog# Purity Size Price Dis. Price Availability Quantity
1P000OYO 98% 5g $13.00 $10.00 In Stock USA ADD TO CART BUY NOW
1P000OYO 98% 25g $18.00 $14.00 In Stock USA ADD TO CART BUY NOW

  • 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1), commonly known as HBTU, is an important reagent in the field of peptide synthesis. It is frequently used as a coupling reagent for the formation of amide bonds, particularly in the synthesis of peptide chains where it facilitates the bonding between amino acid units.
    
    During peptide synthesis, HBTU activates the carboxyl group of one amino acid to make it more reactive towards the amine group of another amino acid. This activation overcomes the poor reactivity that often hampers direct amide bond formation under mild conditions. HBTU, in conjunction with a base like N,N-Diisopropylethylamine (DIPEA), helps in generating an active ester intermediate that can successfully react with an amino component to form a peptide bond without racemization.
    
    Additionally, HBTU is often preferred over other coupling agents such as DCC (Dicyclohexylcarbodiimide) or BOP (Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate) due to its lower toxicity, high efficiency, and the fact that it produces easily removable by-products which simplify purification processes.
    
    The compound is versatile and can be employed not just in peptides, but in other scenarios where creating an amide bond is necessary, like in the synthesis of complex organic molecules, which makes HBTU a valuable tool in medicinal chemistry for the development of pharmaceuticals. The reagent's utility, high yields, and the straightforward nature of the reactions it facilitates make it a staple in many synthesis protocols.

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